24-Hour Urine Collection

To download and print the 24-Hour Urine Collection Instructions, click here.

To download and print the Mid-Stream Clean Catch Urine Collection Instructions, click here.

Laboratory personnel shall provide the collection container for the 24-hour collection to the patient or his representative for our patients.
Laboratory personnel shall provide an instruction sheet for this collection.
Nursing personnel shall collect the specimen and send to the laboratory at collection completion
24-hour urine collections for creatinine clearance must have a serum specimen tested for creatinine during the 24 hours of collection. Submit a blood specimen at same time as the urine.
Some urine chemistry procedures require the patient to be placed on a special diet prior to and/or during the collection of the specimen. The patient should be on the diet for several days prior to starting the collection and remain on the diet until the collection is completed.
Some medications may alter the testing results and should be stopped before and during the collection period as directed by the patient’s physician.
24-hours urine testing is performed at LabCorp.
The following medications and/or foods have been identified by LabCorp to physiologically and/or analytically interfere with the testing. The patient should be appropriately prepared to minimize these interferences.

17-HYDROXYCORTICOSTEROIDS: (analytical interference)
INCREASE:
Acetazolamide	Acetone	Antihypertensives	Ascorbic acid
Carbamazepine	Cefoxitin	Cephalothin	Chloral hydrate
Chlordiazepoxide	Chlormerodrin	Chlorothiazide	Chlorpromazine
Colchicine	Dexamethasone	Digitoxin	Digoxin
Erythromycin	Ethinamate	Etryptamine	Frutose
Glutethimide	Hydroxyzine	Iodides	Meprobamate
Methenamine	Methyprylon	Oleandomycin	Paraldehyde
Penicillin	Perphenazine	Phenazopyridine	Phenothiazines
Piperidine	Potassium iodide	Prochlorperazine	Promazine
Quinidine	Quinine	Spironolactone	Sulfamerazine
Testosterone	Tranquilizers	Vitamin K
DECREASE:
Aspirin	Carbamazepine	Estrogens	Hydralazine
Phenytoin	Prochlorperazine	Promethazine	Reserpine
Salicylate

17-HYDROXYCORTICOSTEROIDS: (physiological interference)
INCREASE:
Betamethasone	Chlorthalidone	Corticotropin	Cortisone
Diethylstilbestrol	Diurnal variation	Ethinyl estradiol	Gonadotropin
Histamine	Metyrapone	Muscular exercise	Sleep deprivation
DECREASE:
Aminoglutethimide	Barbiturates	Blindness	Calcium gluconate
Carbon disulfide	Chlorpromazine	Cothicosteriods	Corticotropin
Dexamethasone	Estrogens	Ethinyl estradiol	Lead
Levodopa	MAO inhibitors	Medroxyprogesterone	Meperidine
Methandrostenolone	Methylethinylestraiol	Metyrapone	Mitotane
Morphine	Norethynodrel	Oral contraceptives	Pentazocine
Perphenazine	Phenobarbital	Phenothiazines	Phenylbutazone
Phenytoin	Progesterone	Promazine	Propoxyphene
Rauwolfia	Reserpine	SKF-12218

5 – HYDROXYINDOLEACETIC ACID (5-HIAA):
INCREASE:
Avocados	Eggplant	Fluorouracil	Melphalan
Methamphetamine	Nicotine	Phenmetrazine	Pineapples
Plums	Pregnancy	Rauwolfia	Reserpine
Sleep deprivation	Smoking	Walnuts
5 – HYDROXYINDOLEACETIC ACID (5-HIAA) continued:
DECREASE:
Aging	Chlorophenylalanine	Corticotropin	Ethanol
Heparin	Hydrazine derivatives	Imipramine	Isocarboxazid
Isoniazid	Levodopa	MAO inhibitors	Methyldopa
Streptozocin

17-KETOGENIC STEROIDS (Analytical)
INCREASE:
Acetazolamide	Acetone	Acetophenon	Cephaloridine
Cephalothin	Chlordiazepoxide	Chlorpromazine	Digitoxin
Etryptamine	Hydralazine	Hydroxyzine	Meprobamate
Methyprylon	Nalidixic acid	Oleandomycin	Paraldehyde
Penicillin	Phenaglycodol	Phenazopyridine	Phenothiazines
Quinine	Sprionolactone
DECREASE:
Chlordiazepoxide	Glucose	Iodipamide	Iothalmate
Meprobamate	Metyrapone	Radiographic acid

17-KETOGENIC STEROIDS (Physiological)
INCREASE:
Ampicillin	Cortisone	Metyrapone
DECREASE:
Ampicillin	Dexamethaxone	Oral contraceptives

17-KETOSTEROIDS (Physiological)
INCREASE:
Aging	Ampicillin	Chlorpromazine	Chlorthalidone
Corticotropin	Danazol	Diurnal variation	Ethinyl estradiol
Gonadotropin	Muscular exercise	Nandrolone	Pregnancy
Testolactone
DECREASE:
Aminoglutethimide	Ampicillin	Betamethasone	Blindness
Carbon disulfide	Chlorpromazine	Corticosteroids	Corticotropin
Cortisone	Fluoxymesterone	Menopause	Meperidine
Methandrostenolone	Metronidazole	Morphine	Noise
Oral contraceptives	Oxcymetholone	Phenothiazines	Phenytoin
Probenecid	Propoxyphene	Pyrazinamide	Spironolactone

METANEPHRINE (Physiological)
INCREASE:
Hydrazine derivatives	MAO inhibitors	Prochlorperazine
DECREASE:
Levodopa

Grandview Medical Center